My pen jaws got worn out and don't hold the blank straight anymore. So I've started turning them round before drilling. I use a centering bit in a hand drill to make a small cone shaped hole in the center of each end. I mount with a 60 degree drive center. Turn round then mount in a collet chuck to drill. Dramatically increases the number of times that I get a hole straight through that is centered on both ends.
Also, I've started using Norseman vortex bits to drill acrylic which much more frequently gives a nice clean exit hole. (Id previously experience blowout sometimes when the bit exits.) the bits are pricy but worth it and you can usually only buy the size you need. Only complaint I have is that I haven't been able to find them I'm jobber length or metric sizes but I can usually work around that. I've also seen some bits billed as acrylic bits that have a much steeper taper on the point. Those would work the same way as the vortex, I think.
Also, I've started using Norseman vortex bits to drill acrylic which much more frequently gives a nice clean exit hole. (Id previously experience blowout sometimes when the bit exits.) the bits are pricy but worth it and you can usually only buy the size you need. Only complaint I have is that I haven't been able to find them I'm jobber length or metric sizes but I can usually work around that. I've also seen some bits billed as acrylic bits that have a much steeper taper on the point. Those would work the same way as the vortex, I think.